Infectious Substance Placard: Where to Buy & Use Correctly

Every shipment of infectious substances sets in motion a chain of responsibility—one that stretches from the loading dock to the open road, and all the way to the final destination. At the heart of this process is a single, unmistakable marker: the Division 6.2 infectious substance placard. More than just a regulatory requirement, this diamond-shaped sign is a frontline defense for public health, ensuring that emergency responders, inspectors, and the public are alerted to the presence of potentially hazardous biological materials. Missing or misused placards can lead to costly compliance violations, shipment delays, and, most importantly, increased risk to people and the environment.

A Division 6.2 placard is not just a formality—it’s a standardized signal that must be displayed on vehicles, containers, and outer packaging whenever infectious materials are in transit. Whether you’re managing regulated medical waste from a hospital, shipping diagnostic specimens from a lab, or overseeing compliance for a logistics fleet, knowing precisely when and how to use these placards is critical.

This article walks you through everything you need to know: the regulatory framework that governs placarding, how to distinguish infectious substance placards from smaller labels, technical specifications you can’t afford to overlook, and where to purchase compliant placards for your operation. Along the way, you’ll learn best practices for application and maintenance, clear up common misconceptions, and find resources to keep your team—and your shipments—in full compliance. By the end, you’ll have a step-by-step guide designed for safety managers, compliance officers, and business owners who can’t afford to get placarding wrong.

What Is an Infectious Substance Placard?

An infectious substance placard is a high-visibility, diamond-shaped hazard sign required on transport vehicles and outer packaging that carry Division 6.2 materials. Its primary role is to alert emergency responders, regulatory inspectors, and the general public to potential biohazard risks during transit. You’ll find these placards on the sides of box trucks hauling Category A specimens from medical labs, on containers filled with regulated medical waste from hospitals, and on crates of research samples bound for biotech facilities.

Definition and Purpose

An Infectious Substance Placard is a standardized, diamond-shaped sign that identifies Division 6.2 (infectious) materials under U.S. and international hazardous materials regulations. Beyond regulatory compliance—DOT, IATA, ADR and others—it serves as a critical safety communication tool. By displaying the placard, shippers signal first responders and inspectors that they’re handling potentially life-threatening pathogens.

Real-world example: A virology lab shipping UN 2814 Ebola samples must affix a Class 6.2 placard to the outer package and transport vehicle. In the event of an accident or spill, responders immediately recognize the extreme hazard level and deploy the right protective procedures.

Applicable Regulations

Placarding infectious substances is not optional—it’s mandated by multiple regulatory frameworks:

49 C.F.R. Parts 171–180 (HMR): U.S. Highway, rail, water, and air transport rules, including § 172.500 for placard display thresholds.
IATA Dangerous Goods Regulations: Air transport requirements for Category A/B specimens and crew training mandates.
ADR (European road/rail): Consistent diamond-shaped placard specs for cross-border shipments.
IMDG Code: Marine transport standards, including sea-immersion durability tests.
ICAO Technical Instructions: Air transport rules that align with IATA but also cover security and stowage.

Visual Characteristics

Infectious substance placards share a common design to ensure instant recognition:

Feature	Specification
Background color	Pantone 151c / Hex #FF7900
Border thickness	6 mm
Biohazard symbol size	Minimum 100 mm diameter
Placard dimensions	250 mm × 250 mm
Optional text	“INFECTIOUS SUBSTANCE” below symbol

Every element—from the bold orange background to the black border and biohazard emblem—follows strict standards. This consistency helps emergency personnel identify the risk quickly, whether by daylight or under low-light conditions when reflective materials come into play.

Regulatory Requirements for Placarding Infectious Substances

Navigating the maze of hazmat rules can feel overwhelming, but understanding the core regulations is the key to smooth, compliant transport. Whether you’re moving samples down the highway, booking air freight, or shipping by sea, these mandates spell out exactly when and how an infectious substance placard must be displayed. Below, we break down U.S. requirements, delve into PHMSA guidance, and touch on the major international rules that apply.

DOT’s Hazardous Materials Regulations (49 CFR Parts 171–180)

Under the U.S. Hazardous Materials Regulations (HMR), found in 49 C.F.R. Parts 171–180, any transport of infectious substances by highway, rail, water, or air must follow specific placarding rules. Section §172.500 sets the stage:

When to placard: You need placards on any transport unit (vehicle or freight container) if you carry 454 kg (1,001 lbs) or more of Division 6.2 materials.
How to placard: The standard 250 mm × 250 mm diamond goes on all four sides, between 0.6 m and 4 m above the ground, and in a spot that’s free from obstructions.
Specifications: Colors, symbols, and text must meet the criteria in §172.519 (orange background, black biohazard emblem, optional “INFECTIOUS SUBSTANCE” legend).

Failure to meet these display requirements can trigger fines, shipment delays, or even a recall of the load.

PHMSA Guidance for Infectious Substances

The Pipeline and Hazardous Materials Safety Administration (PHMSA) provides a handy brochure—Transporting Infectious Substances Safely—that distills key HMR provisions for Category A and Category B shipments. Highlights include:

Classification rules: Category A (UN 2814/UN 2900) vs. Category B (UN 3373) definitions and packing thresholds.
Packaging and marking: Overview of the triple packaging system, required markings, and documentation like the Shipper’s Declaration for dangerous goods.
Recordkeeping: Retention periods for shipping papers and emergency response information.

Consulting PHMSA’s guidance helps ensure you’re applying the right placards, labels, and shipping papers for each type of infectious material.

IATA Dangerous Goods Regulations for Air Transport

Air shipments of infectious substances are governed by the IATA Dangerous Goods Regulations (DGR). The two most relevant packing instructions are:

Packing Instruction 620: For Category A (UN 2814, UN 2900) samples.
Packing Instruction 650: For Category B (UN 3373) specimens.

In addition to standard placarding on ground transport segments, the IATA DGR requires:

Proper labels: Use the IATA-approved “Infectious Substance” diamond on the outer package.
Shipper’s Declaration: Mandatory for all Category A consignments.
Training: Anyone handling or preparing these shipments must complete recurrent dangerous goods training at least every two years.

For full details, see the IATA DGR manual on the IATA website.

Other International Regulations (ADR, IMDG, ICAO-TI)

When you cross borders or switch modes, these additional rules come into play:

ADR (European road/rail): Lays out placarding thresholds (e.g., 333 kg total gross mass) and design specs for diamonds used across the EU.
IMDG Code (sea): Requires placards and labels that withstand a three-month sea-immersion test, plus specific loading and stowage provisions.
ICAO Technical Instructions (air): Align closely with IATA but add stowage, segregation, and security requirements unique to civil aviation.

By keeping these regulations in mind, you’ll know exactly which placard to use—and when—to stay compliant around the globe.

Classification of Infectious Substances (Category A vs Category B)

Knowing how to classify your material is the first step in selecting the right placard and packaging system. The DOT and international regulations divide infectious substances into two main categories—A and B—based on their risk level. Understanding these distinctions helps you assign the correct UN number, apply appropriate labels, and meet all placarding requirements.

Category A: Criteria and Examples

Category A covers the highest-risk infectious substances: those in a form capable of causing permanent disability, life-threatening illness, or death in otherwise healthy humans or animals upon exposure. These materials require the most stringent controls in every phase of transport.

UN Numbers
- UN 2814: Infectious substances affecting humans
- UN 2900: Infectious substances affecting animals
Key Characteristics
- Potential for severe health impacts
- Strict packaging under IATA Packing Instruction 620 and HMR triple packaging rules
- Mandatory Shipper’s Declaration for dangerous goods
Real-World Examples
- Ebola virus samples (UN 2814)
- Anthrax spores (UN 2814 or UN 2900, depending on host)
- Foot-and-mouth disease virus (UN 2900)

Because of the extreme hazard, Category A shipments must display a Class 6.2 placard on any transport unit carrying 454 kg (1,001 lbs) or more of these materials, and individual packages must bear the “Infectious Substance” diamond label.

Category B: Criteria and Examples

Category B includes lower-risk substances that still pose health risks but are not generally capable of causing permanent disability or death in healthy individuals when exposure occurs. These are mostly diagnostic or clinical specimens.

UN Number
- UN 3373: Biological specimens
Key Characteristics
- Typically diagnostic samples such as blood, urine, or swabs
- Subject to less rigid packaging (IATA Packing Instruction 650)
- No Shipper’s Declaration required, but the triple packaging system still applies
Real-World Examples
- Routine blood tests sent from a clinic
- Urine samples for laboratory analysis
- Nasal swabs for viral screening

For Category B shipments, placards are generally not required unless you exceed the 454 kg threshold for Division 6.2 materials in a single transport unit. Instead, each outer package must carry the UN 3373 label.

Regulated Medical Waste

Regulated medical waste (RMW) overlaps with infectious substances but follows slightly different rules under DOT and OSHA. RMW includes any waste or reusable materials derived from medical treatment of humans or animals, such as used sharps, contaminated dressings, and discarded cultures.

Regulatory Framework
- DOT treats RMW as a hazardous material when it meets the definition of an infectious substance
- OSHA’s bloodborne pathogens standard requires biohazard markings on waste containers in healthcare settings
Key Distinctions
- RMW may be exempt from Division 6.2 placarding if it only bears the OSHA biohazard symbol, rather than the “Infectious Substance” label
- When in doubt, classify RMW as UN 2814/UN 2900 or UN 3373 based on its potential risk and follow the corresponding placarding rules

For shipments that include regulated medical waste destined for disposal or treatment facilities, always verify whether the biohazard symbol alone suffices or if a full Class 6.2 placard is necessary. This ensures both compliance and clarity for handlers and emergency responders.

Understanding Placard vs. Label: What’s the Difference?

When moving infectious materials, it’s easy to confuse the smaller hazard labels you stick on individual packages with the larger placards that adorn transport vehicles and bulk containers. Labels and placards share the same diamond-shaped design and biohazard symbol, but they serve different purposes, follow different size specifications, and kick in under different circumstances. Knowing which to use— and when—keeps shipments compliant, avoids costly fines, and helps first responders quickly assess risks.

At a glance, hazard labels are meant for single packages or small outer containers. Placards, on the other hand, warn of Division 6.2 materials in larger quantities across an entire transport unit. Below, we break down the requirements for both and point out scenarios where one is enough or both are required.

Labeling Requirements for Packages

Hazard labels identify infectious substances at the package level. They’re standardized diamond-shaped markings—100 × 100 mm or, in confined shipments, as small as 50 × 50 mm—bearing the black biohazard symbol on an orange background.

Key points for package labels:

Size and design:
- Standard: 100 × 100 mm
- Small shipments (limited/exempt): 50 × 50 mm
Placement: On the outermost package layer where it’s clearly visible alongside the UN number (e.g., UN 3373) and proper shipping name.
Use cases: Each box of diagnostic specimens (Category B) or individual container of Category A samples must carry the corresponding label. No placard is needed if the entire load stays below the placarding threshold.

Placarding Requirements for Vehicles and Bulk Containers

Placards signal that an entire vehicle or freight container carries a regulated quantity of Division 6.2 materials. These signs measure 250 × 250 mm, with a 6 mm black border and a bold biohazard emblem on Pantone 151c (Hex #FF7900).

When to apply placards:

Quantity trigger: 454 kg (1,001 lbs) or more of infectious substances on a single transport unit.
Transport modes: Required on highway trailers, rail cars, and sea-going containers once you exceed the weight or volume threshold.
Vehicle display: One placard on each side and one on the front and rear—four total.

Without these signals, emergency responders might underestimate the risk during a spill or accident, so it’s crucial to apply placards once your shipment meets regulatory triggers.

When Placards Are Not Required

Not every shipment of infectious substances needs placards. Exceptions include:

Small loads of Category B (UN 3373) specimens under the 454 kg threshold.
Exempt human or animal specimens that fall under “excepted quantity” rules.
Single-package shipments arranged with a courier or mail service, provided they meet IATA Packing Instruction 650 limits.

For example, sending a single box of routine blood samples from a clinic rarely demands a vehicle placard—just the proper UN 3373 label on the package.

Placard Placement and Visibility Standards

Once placarding is mandatory, follow these display rules:

Location: Centered on all four sides of the transport unit, between 0.6 m and 4 m above ground.
Visibility: Avoid placing placards over hinges, door handles, or areas that get obstructed by loading equipment.
Reflectivity: Use reflective material or add illumination for night transport so that symbols remain legible under headlights.
Maintenance: Inspect placards regularly for peeling, fading, or damage, and replace any that compromise visibility.

By sticking to these guidelines, you ensure first responders and inspectors instantly recognize the presence of infectious substances—day or night—and take the appropriate safety measures.

Specifications for Division 6.2 Infectious Substance Placards

Choosing the right Division 6.2 placard goes beyond grabbing the boldest orange diamond off the shelf. To stay compliant and keep your shipments safe, every detail—size, color, material, and adherence to industry standards—must meet statutory requirements. A correctly made placard is your first line of defense in an emergency: from standardized dimensions to fade-resistant inks, these specs ensure first responders can spot and interpret the hazard immediately, day or night.

Size, Color, and Symbol Requirements

The visual consistency of infectious substance placards is non-negotiable. Regulations prescribe:

Placard dimensions: Minimum 250 mm × 250 mm (10″ × 10″).
Border thickness: 6 mm solid black frame.
Background color: Orange, Pantone 151c (Hex #FF7900).
Biohazard symbol: Solid black, at least 100 mm (4″) diameter, centered.
Optional text: “INFECTIOUS SUBSTANCE” in uppercase beneath the symbol, using a clear sans-serif font.

These parameters guarantee that the placard remains instantly recognizable, even at a distance or under low-light conditions when combined with reflective materials.

Material and Durability Standards

Placards must withstand harsh environments—from blistering sun to saltwater spray—without losing legibility. Common materials include:

Vinyl self-adhesive: Flexible, easy to apply, with UV-resistant, weather-proof laminate.
Laminated paper: Economical for short-term use; meets basic HMR specs but may fade sooner.
Enamel-coated aluminum: Rigid and highly durable, resisting abrasion, chemicals, and corrosion.

Essential durability tests and attributes:

UV resistance: Materials and inks should endure 2–3 years of sunlight without significant fading.
Water immersion: Must pass a three-month sea-immersion test per the IMDG Code.
Temperature range: Stable performance between –30 °C and +60 °C (–22 °F to +140 °F) without cracking or peeling.

Compliance with ANSI, ISO, and OSHA Standards

Infectious substance placards also align with established safety-sign standards:

ANSI Z535 series: Defines hazard symbol design, color codes, and safety communication for workplace signs.
ISO 3864-2: Specifies colors, shapes, and layout for safety signage used internationally.
OSHA bloodborne pathogens rule (29 C.F.R. 1910.1030): Mandates biohazard symbols on containers and equipment handling infectious materials.

Meeting these benchmarks ensures your placards comply with DOT, IATA, and ADR regulations and integrate seamlessly into your broader safety program.

How to Use an Infectious Substance Placard Correctly

Applying and maintaining your infectious substance placard might seem straightforward, but a few missteps can compromise compliance—or worse, safety. Follow these practical steps to ensure your placards communicate risks clearly and hold up to the rigors of transport.

Placement on Vehicles and Containers

Proper placement guarantees that first responders and inspectors spot the placard immediately. Here’s a quick how-to:

Prepare the surface
- Clean the panel with a mild detergent or isopropyl alcohol.
- Make sure the area is dry and free of grease, wax, or dirt.
Position the placard
- Center each 250 × 250 mm placard on the side panels, front, and rear of the vehicle or container.
- Maintain a height between 0.6 m (2 ft) and 4 m (13 ft) from the ground.
Apply and smooth
- Peel off the backing and press the placard starting from the center.
- Use a squeegee or firm hand pressure to work out air bubbles and ensure full adhesion.
- Check that borders aren’t cut off by hinges, handles, or door gaps.

Grouping Rules for Multiple Hazards

Sometimes you’re hauling more than infectious substances—perhaps corrosive chemicals or flammable liquids too. In those cases:

Display one placard for each hazard class present (e.g., Class 6.2 and Class 8).
Place placards side by side on each panel, maintaining equal spacing and height.
If you have four sides but three hazards, repeat the most severe hazard on the fourth side.

For example, a truck carrying both infectious specimens and corrosive acids must show a Class 6.2 placard and a Class 8 placard on all applicable sides. This layered approach gives responders a complete picture of potential risks at a glance.

Orientation, Maintenance, and Inspection

Even the best-made placard won’t serve its purpose if it’s faded, peeling, or obscured. Build a routine around these checks:

Pre-trip inspection: Before every run, walk around the vehicle to confirm each placard is present, legible, and free from damage.
Monthly audit: Once a month, document the condition of each placard with photos and notes. Look for:
- Fading or discoloration
- Lifting edges or cracks
- Dirt build-up or residue that covers the symbol
Replacement triggers: If the biohazard symbol or text is less than 90% intact, or if the placard doesn’t stick securely, swap it out immediately.

Keeping a simple log—date, inspector’s name, and a quick status check—helps demonstrate compliance during audits and keeps your team in the habit of treating placards as mission-critical safety gear.

Packaging and Labeling Requirements for Infectious Substances

Packaging and labeling go hand in hand with placarding when you ship infectious materials. A sound packaging strategy protects both the substance and anyone handling it, while clear labeling communicates hazards at every step. Below, we’ll cover the triple packaging system you must use, how to mark packages with the proper UN information, and best practices for orientation arrows and biohazard symbols.

Triple Packaging System

Regulations mandate a three-layer approach to containing infectious substances. First, the primary receptacle holds the specimen—this could be a sealed vial or leakproof plastic bag. If the sample is liquid, you’ll include enough absorbent material (at least 100 % of the liquid volume) between the primary and secondary layers. Next, the secondary container is a sturdy, watertight closure such as a cushioned box or hard plastic case that keeps the primary receptacle from shifting. Finally, the outer package is a rigid box or crate that protects against rough handling and environmental extremes.

Each layer must meet specific performance tests—drop, vibration, and compression—to ensure integrity in transit. The outer package also needs enough cushioning so that, even if the primary receptacle fails, the absorbent material traps any leak. Following this system not only satisfies DOT and IATA rules but also gives everyone from warehouse staff to customs inspectors the confidence that the material is secure.

Marking with UN Number and Proper Shipping Name

Once your sample is safely packaged, the next step is clear marking. Every outer package must display the UN number (for example, UN 2814 or UN 3373) and the proper shipping name (“Infectious substance, affecting humans” or simply “Biological substance, Category B”). These details sit adjacent to the infectious substance label—usually to the right or directly below—to form a neat, readable block of information.

Here’s a typical layout:

Top left: Shipper’s name and address
Top right: Consignee’s name and address
Center: Infectious substance label (100 × 100 mm)
Bottom: “UN 3373” on one line, “Biological substance, Category B” on the next

By spacing these elements consistently, you make it easy for carriers, inspectors, and emergency responders to parse critical data at a glance. Remember also to include any additional marks required by IATA Packing Instructions 620 or 650, such as “Temperature controlled” or air waybill numbers.

Orientation Arrows and Biohazard Symbol Usage

For liquid specimens, orientation arrows play a big role in preventing spills. Place a pair of black arrows (at least 100 mm tall) on opposite sides of the outer package, pointing upward. These arrows must be at least 12 mm thick and spaced so that they’re visible even if one side is blocked. This helps handlers keep vials upright and absorbent pads on top of potential leaks.

The biohazard symbol itself must comply with ISO 7000-B015, featuring three interlocking circles around a central ring. On package labels, the symbol should be at least 50 mm in diameter; on placards, we already saw it’s a minimum of 100 mm. Use a solid black symbol on the orange background specified earlier, and never reduce its size or alter its proportions. Consistent symbol placement—centered within its diamond—ensures universal recognition and a swift, coordinated response in case of an incident.

Where to Buy Division 6.2 Infectious Substance Placards

When it comes to sourcing compliant Division 6.2 placards, turning to established suppliers ensures you get materials that meet DOT, IATA, and international standards. Whether you need bulk orders for a nationwide fleet or specialty labels for a single container, these vendors have you covered.

Major Reputable Suppliers and Their Offerings

JJKeller
Offers wordless vinyl placards that adhere to international Division 6.2 specifications. These self-adhesive, permanent vinyl labels resist UV fading and chemical exposure, making them ideal for long-haul or maritime shipments.
JJKeller Division 6.2 Infectious Substances – Wordless
AirSea Containers
Specializes in durable DOT placards designed to withstand UV rays, moisture, and abrasion. Their 250 × 250 mm vinyl placards include a protective laminate, perfect for multimodal transport.
AirSea Infectious Placard
SERPAC
Provides a broad lineup of labels and placards for both Category A (UN 2814/UN 2900) and Category B (UN 3373) shipments. Materials range from paper and polyethylene to rigid PVC and reflective sheeting that pass IMDG sea-immersion tests.
SERPAC Class 6.2 Infectious Substances
ComplianceSigns
Features enamel-coated aluminum and semi-rigid PVC placards with high reflectivity, suitable for industrial environments and long-term outdoor use.
ACCUFORM
Offers customizable placards and labels, including magnetic mounts and tamper-evident options—ideal for leased vehicles or quick-change applications.
Safety Emporium
Stocks blank DOT Class 6 placards with space for custom 4-digit UN numbers, available in polycoated tagboard and semi-rigid PVC.

Customization Options and Specialty Suppliers

Off-the-shelf won’t always cut it. If you need something unique:

Request nonstandard sizes beyond 250 × 250 mm for unusual container dimensions.
Opt for reflective or illuminated backings to boost nighttime visibility.
Choose magnetic or peel-and-stick versions for fast installation and removal on rental equipment.

Many regional print shops and certified small businesses can turn around custom runs in days rather than weeks, helping when deadlines are tight.

How to Verify Vendor Compliance and Certifications

Before placing an order, confirm your supplier can back up their product claims:

Ask for UN test reports demonstrating durability under packaging and placarding stress tests.
Request IMDG sea-immersion certificates and UV resistance data.
Verify adherence to ANSI Z535 and ISO 3864 standards for symbol accuracy and color.
Review material datasheets covering substrate composition, thickness, and performance across –30 °C to +60 °C.

Suppliers who readily share this documentation are more likely to deliver placards that pass inspections and keep your shipments moving without hiccups.

Cost and Material Considerations When Purchasing Placards

Balancing upfront cost with long-term durability is key when you’re outfitting a fleet or ordering a handful of placards for occasional use. Material choice, order volume, and the trade-off between price and performance will directly affect your budget and compliance reliability. Below, we break down typical materials, illustrate how unit prices shift with order size, and highlight scenarios where investing a bit more up front can save replacement costs down the road.

Material Types and Their Price Ranges

Different substrates deliver varying levels of durability—and price points. Here’s a quick comparison of common placard materials:

Material	Unit Cost (USD)	Expected Lifespan
Laminated Paper	$1.00 – $2.00	6–12 months
Vinyl Self-Adhesive (PE)	$2.00 – $5.00	2–3 years
Rigid PVC	$4.00 – $8.00	3–5 years
Enamel-Coated Aluminum	$8.00 – $15.00	5–10 years

Laminated paper is the most budget-friendly but may fade or peel in under a year. Vinyl self-adhesive strikes a balance for medium-term use, while PVC and aluminum placards withstand harsher environments and require less frequent replacement.

Bulk vs. Single-Unit Pricing

Ordering in volume can unlock significant savings. Suppliers often offer tiered discounts that look something like this:

Single unit: base price (no discount)
Pack of 10–50: 10–15% off per placard
Case of 100+: 20–30% off per placard

For example, a vinyl self-adhesive placard priced at $4.50 each might drop to $3.80 when you buy 25, and further to $3.15 in a 100-unit case. If you’re deploying placards across multiple vehicles—or stocking spares for routine replacement—these bulk discounts quickly offset storage costs and help you maintain compliance without breaking the bank.

Durability vs. Cost Trade-offs

Opting for the cheapest placard isn’t always the wisest choice. Think of it this way:

Short-term projects or one-off shipments: Laminated paper may suffice, even if it needs replacing after 6–12 months.
Regular highway or maritime hauls: Vinyl self-adhesive delivers UV and water resistance at a moderate price.
Industrial-strength environments or long-term fixtures: Enamel-coated aluminum offers the lowest lifetime cost per year of service, despite a higher initial outlay.

By aligning material selection with your specific use case, you avoid frequent replacements, downtime, and potential non-compliance fines—turning a higher upfront investment into a smarter long-term decision.

Best Practices for Storage, Inspection, and Replacement of Placards

Proper storage, regular inspection, and timely replacement of Division 6.2 placards keep your fleet compliant and your team safe. A well-maintained placard retains its vibrant color and adhesive strength, ensuring that emergency responders and inspectors recognize potential biohazards at a glance. Below, you’ll find practical guidance on how to store placards correctly, conduct routine checks, and swap out worn or damaged signs without missing a beat.

Storage Conditions to Prolong Placard Life

Storing placards in the right environment goes a long way toward preserving their performance:

Indoor, climate-controlled space
Keep placards away from direct sunlight, extreme heat, and high humidity. Temperatures between 50 °F and 75 °F help prevent warping and adhesive breakdown.
Flat, clean racks or shelves
Store sheets or rolls flat to avoid curling at the edges. If placards are rolled, use a core with a diameter of at least 3 inches so the vinyl or paper doesn’t crease.
Dust-free environment
Dust particles can scratch or embed under a placard’s surface. Cover stored placards with a clean cloth or place them in sealed bins to minimize contaminants.
Away from chemicals
Solvents, oils, and strong cleaning agents can attack inks and adhesives. Keep placards in a separate area from industrial chemicals and maintain clear labeling on storage shelves.

Following these storage tips means when it’s time to apply a placard, it looks—and sticks—like new.

Routine Inspection Checklist

A quick daily scan and more thorough monthly review help spot issues before they become compliance headaches. Incorporate these steps into pre-trip and facility-wide safety inspections:

Daily (Pre-Trip)

Verify each placard is present on all four sides of the vehicle or container.
Check for obvious damage: tears, creases, or missing corners.
Confirm the biohazard symbol and any text remain sharp and legible.

Monthly (Documented Audit)

Measure reflectivity under low light or with a flashlight—ensure the symbol still “pops” in dim conditions.
Look for fading: if orange appears washed out or the black border has thinned, flag for replacement.
Test adhesion: gently tug a corner; if it lifts easily, plan to reapply.
Record findings in a simple log (date, inspector, condition notes, photo if possible).

Keeping a routine not only extends placard life but also demonstrates diligence during regulatory reviews.

When and How to Replace Damaged or Faded Placards

Even high-quality materials eventually give way to wear. Replace placards when you notice:

Significant discoloration or UV fading (colors appear dull or patchy).
Structural damage: cracks, tears, or lifting edges.
Loss of adhesion: curling corners or entire placard peeling off.
Compromised reflectivity under night-time inspection.

Replacement steps:

Remove the old placard: Peel back one corner and pull slowly. Use an adhesive remover (e.g., isopropyl alcohol) to clear residue.
Clean the surface thoroughly: Wipe with a lint-free cloth and a mild detergent solution or isopropyl alcohol. Let the area dry fully.
Reapply a new placard: Center it in the same position, press from the middle outward, and smooth out any bubbles with a squeegee or firm hand pressure.
Verify alignment and adhesion: Give it a final once-over—make sure borders aren’t cut off and edges are flush.

By swapping out worn placards promptly, you maintain clear hazard communication and avoid fines or shipment holds. Regular maintenance like this keeps your operation running smoothly and your team confident that every load meets safety standards.

Common Questions About Infectious Substance Placards

Below are answers to some of the most frequently asked questions about Division 6.2 infectious substance placards. These quick references can help you ensure proper hazard communication and avoid compliance missteps.

What placard is used for infectious substances?

The placard used for infectious substances is the Hazard Class 6.2 “Infectious Substance” diamond‐shaped sign. It measures at least 250 × 250 mm, features an orange background (Pantone 151c), a 6 mm black border, and the solid black biohazard symbol in the center. Common substrates include:

Vinyl self-adhesive with UV-resistant lamination
Rigid PVC panels for repeated use
Enamel-coated aluminum for the longest lifespan

These durable materials ensure the placard remains legible under sun, rain, and rough handling, alerting responders to biohazard risks promptly.

What is a 6.2 infectious substance?

A Division 6.2 infectious substance is any material known or reasonably expected to contain pathogens—microorganisms like bacteria, viruses, or parasites—that can cause disease in humans or animals. Under the UN/DOT classification system:

Class 6 covers “Toxic and infectious substances.”
Division 6.2 specifically designates “Infectious substances.”

This division includes both high‐risk agents (Category A, UN 2814/UN 2900) and lower‐risk diagnostic specimens (Category B, UN 3373). Classifying your material correctly determines packaging, labeling, and placarding requirements.

What hazard class is an infectious substance?

Infectious substances fall under Hazard Class 6.2 in both the UN model regulations and U.S. DOT’s Hazardous Materials Regulations (49 C.F.R. Parts 171–180). Class 6 is split into:

Division 6.1: Toxic substances
Division 6.2: Infectious substances

When you see the Class 6.2 label or placard, you know it marks materials capable of transmitting pathogens that pose health risks during transport.

Do Division 6.2 infectious substances require placards?

Not always. Placarding becomes mandatory when a single transport unit carries 454 kg (1,001 lbs) or more of Division 6.2 materials, as specified in §172.500 of the HMR. Below that threshold, individual outer packages still need the proper 100 × 100 mm “Infectious Substance” label but do not require vehicle-level placards.

Common exceptions include:

Category B (UN 3373) specimens under 454 kg total
Excepted or limited quantities that meet IATA Packing Instruction 650 limits
Single-package shipments via courier or mail that comply with small-quantity rules

Understanding these triggers ensures you apply labels and placards correctly—no more, no less—keeping shipments compliant and safe.

Additional Resources for Compliance and Further Reading

Navigating the complex requirements for transporting infectious substances calls for reliable, up-to-date references. Below is a curated list of official guidance, training programs, and practical templates that can help safety managers and compliance teams stay on track and audit-ready.

Official Government and International Resources

• PHMSA’s Transporting Infectious Substances Safely Brochure
A concise guide that distills key HMR provisions for Category A and B shipments, covering classification, packaging, marking, and recordkeeping. Access it here: https://www.phmsa.dot.gov/transporting-infectious-substances/transporting-infectious-substances-safely

• IATA Dangerous Goods Regulations (DGR) Manual
The definitive rulebook for air transport of infectious substances, including Packing Instructions 620 (Category A) and 650 (Category B), labeling standards, Shipper’s Declaration templates, and training requirements. Available on the IATA website: https://www.iata.org/en/publications/dgr/

• Centers for Disease Control and Prevention (CDC) Guidance
Authoritative recommendations on handling, packaging, and biosafety practices for infectious materials before and after transport.

• OSHA Bloodborne Pathogens and PPE Standards
Regulations that protect workers from exposure to infectious substances, including required biohazard markings in healthcare and laboratory settings.

Training and Certification Programs

• DOT Hazmat Training
Required under 49 C.F.R. § 172.704 for anyone who handles or prepares hazardous materials shipments. Look for PHMSA-approved providers offering initial and recurrent courses.

• IATA Dangerous Goods Certification
Specialized courses on the DGR manual, including modules on infectious substance handling, labeling, and Shipper’s Declaration completion. Revalidation is required every two years.

• Internal Workshops and Tabletop Exercises
Develop in-house drills that simulate spill response, placard inspection, and documentation audits. These practical sessions build team confidence and reinforce regulatory know-how.

Templates and Sample Documents

To streamline shipment preparation and support audits, maintain a library of standard forms and artwork files:

Shipper’s Declaration of Dangerous Goods templates as prescribed by PHMSA and IATA
DOT shipping paper samples that include emergency response information and retention requirements
Placard and label artwork in vector or high-resolution formats for accurate printing
Sample packing lists and triple-packaging checklists to document compliance with HMR and IATA Packing Instructions

Most of these templates can be downloaded directly from the PHMSA forms library or extracted from the IATA DGR manual. Having them on hand will speed up your workflow and ensure consistency across every shipment.

Next Steps for Ensuring Proper Placarding

Now that you understand the regulatory requirements, classification distinctions, and technical specifications for an infectious substance placard, it’s time to put that knowledge into action. Effective placarding isn’t a one-off task—it’s an ongoing process of assessment, procurement, application, and maintenance. Follow these practical next steps to keep your shipments compliant, your team confident, and your operation running smoothly.

Here’s a quick checklist to guide your next moves:

Classify Your Material
Confirm whether you’re dealing with Category A (UN 2814/UN 2900) or Category B (UN 3373) substances. Accurate classification is the foundation for selecting the right packaging, labels, and placards.
Select the Correct Placard
Decide between a 250 × 250 mm Class 6.2 placard and smaller package labels. Remember the 454 kg (1,001 lb) threshold for vehicle-level placarding under §172.500.
Verify Vendor Credentials
Source placards from reputable suppliers and request UN test reports, IMDG sea-immersion certificates, and compliance with ANSI Z535 and ISO 3864 standards.
Choose Durable Materials
Match your environment to the material—vinyl self-adhesive for medium-term use, PVC or aluminum for long-term, high-abuse settings.
Implement an Inspection Routine
Build a simple log for daily pre-trip checks and monthly audits. Look for fading, peeling, and adhesion issues, and swap out any compromised placards immediately.
Train Your Team
Provide refresher sessions on placard placement, grouping rules, and maintenance. A well-prepared crew minimizes errors and ensures safety from pickup to delivery.

By following these steps, you’ll turn the theory of placarding into a reliable practice that safeguards public health, streamlines your operations, and shields you from costly compliance penalties.

Ready to simplify your placarding process? Reach out to Safety Decals for custom infectious substance placard solutions and expert regulatory support tailored to your needs. Our team is here to help you select the right materials, design compliant graphics, and implement best practices—so you can focus on what matters most: moving critical materials safely.